Sue Ann is a loner who keeps to herself in her quiet Ohio town. One day, she is asked by Maggie, a new teenager in town, to buy some booze for her and her friends, and Sue Ann sees the chance to make some unsuspecting, if younger, friends of her own.

The aristocratic, wealthy France-born Boudine family move to New Orleans in the mid-1800s to make their way in America. Then their beautiful youngest daughter cross paths with the fiancé of the legendary Queen of Louisiana Voodoo, Marie Laveau. They have a baby and try to keep it a secret, but Madame Laveau finds out and decides that the entire family deserves the focus of Laveau's most destructive curse.